However, insulin use forces them to contend with many daily training and performance challenges involved with fine-tuning medication dosing, physical activity levels, and dietary patterns to optimize their participation and performance. Individuals with type 1 diabetes (T1D) are able to balance their blood glucose levels while engaging in a wide variety of physical activities and sports.
Whether this is a cause or effect of hypoglycaemia remains to be established. Increasing carbohydrate intake while decreasing that of fats, is associated with higher hypoglycaemia risk. In conclusion, refraining from alcohol intake is a preventable risk factor for DKA, while higher fibre intake seems rather protective. Substituting carbohydrates for fats was associated with increased risk for hypoglycaemia hospitalisation (B = 1.361, 95% CI = 1.031–1.795, p = 0.029), while substituting alcohol for carbohydrates (B = 1.644, 95% CI = 1.006–2.685, p = 0.047) or proteins (B = 2.278, 95% CI = 1.038–4.999, p = 0.040) increased the risk for DKA hospitalisation. Data were available from 1391 participants, 28 (2.0%) and 55 (4.0%) of whom were hospitalised due to DKA or hypoglycaemia, respectively. Analyses were conducted with and without macronutrient substitution. Data on DKA and hypoglycaemia hospitalisations, within two years of dietary assessments, were obtained from registries. Food records were used to assess dietary intake. We investigated the association between diet and risk of hospitalisation for diabetic ketoacidosis (DKA) or hypoglycaemia in type 1 diabetes. Over 80% of type 1 adolescents had hypoglycemia in a week, which may be attributed to the mismatch between optimal insulin dose needed for each meal and actually delivered insulin dose without considering quality of carbohydrate and nutrients beyond carbohydrate.Ĭ identifier: NCT01286350. Adjusting for total daily insulin dose per kilogram eliminated all associations.ĭietary intake was differentially associated with daytime and nocturnal hypoglycemia. Glycemic index, monounsaturated fat, and polyunsaturated fat were negatively associated with daytime hypoglycemia only. Soluble fiber and protein intake were positively associated with both daytime and nocturnal hypoglycemia.
Data were analyzed using logistic regression models.Īmong 98 participants with 14,277h of CGM data, 70 had daytime hypoglycemia, 66 had nocturnal hypoglycemia, 55 had both, and 17 had neither. Non-severe hypoglycemia was defined as having blood glucose <70mg/dL for ≥10min but not requiring external assistance, categorized as daytime and nocturnal (11PM-7AM). Dietary intake was calculated as the average from two 24-h dietary recalls.
Lp hipoglikemia pdf trial#
Type 1 adolescents from a randomized trial wore a blinded continuous glucose monitoring (CGM) system at baseline for one week in free-living conditions. To determine the association between dietary intake and risk of non-severe hypoglycemia in adolescents with type 1 diabetes.
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